The DIAN Trials Unit (DIAN-TU) platform implements interventional therapeutic trials for at-risk families with DIAD, focusing on drugs that can potentially change the course of the disease.

Two types of DIAN-TU trials

The DIAN-TU site staff will determine which study is best suited for each potential participant, based on their estimated years to (symptom) onset, or “EYO”. A person’s EYO takes into consideration the actual age of the participant and the age at which their parent or relative became symptomatic.

Primary Prevention Trial

These trials seek to intervene before amyloid plaques form in the brain. 

Secondary Prevention Trials

These trials are studies aimed at stopping a disease from getting worse or causing further harm once it has already been detected.

Recent Publications

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DIAN-TU Support

Randall Bateman, MD

Principal Investigator & Program Director

Eric McDade, DO

DIAN-TU Co-director, Investigator

Leadership & Team Members

Study Team | Funding | History

Study details (DIAN-TU-001) on clinicaltrials.gov


For Investigators

Visit Investigator Resources for information on accessing resources and participation policies.