Update on the DIAN-TU-001 TRIAL

Update on the DIAN-TU-001 TRIAL:  Janssen BACE Inhibitor (JNJ-54861911/atabecestat) DRUG ARM DISCONTINUATION The statement below is an update to the May 25th announcement found on Janssen’s website. Previously, Janssen observed elevations of liver enzymes in some study participants who received atabecestat, including two patients who had high elevations of liver enzymes, placing them at increased […]

DIAN-TU Trial Interim Analysis

Notice to DIAN-TU Investigational Sites and Participants RE: DIAN-TU-001 INTERIM ANALYSIS April 25, 2018 DIAN-TU Site Leaders and Participants, The original goal and intent of the biomarker interim analysis was to determine if the investigational drugs at the dosages used were modifying the amyloid-beta targets.  The biomarker Interim Analysis was designed to allow the DIAN-TU […]